Extra Crispr

Every few months we get a blazing headline about a breakthrough in genetics that will allegedly lead to super babies. This one from a few months ago is a good example of the genre. It makes for a catchy headline. Of course, the story is never as claimed, as we are not close to creating a race of mutant super babies. Instead, science is creeping up on the ability to do some very narrow gene editing to eliminate well known genetic defects. In fact, a lab has just successfully edited a viable embryo for the first time.

This is a huge step in science, but we are nowhere near close to creating the master race or even making small changes in real humans. The most recent research on human intelligence, for example, identifies 50 genes that correlate to IQ. That’s a lot of combination to sort, assuming that is the whole set of genes related to IQ. There’s also the possibility that other traits are indirectly related to those genes. Even something as simple as hair color can get wildly complex, so we will not be decanting babies anytime soon.

While we are nowhere near close to making super babies, this is one step down the road toward altering the foundations of human existence. The ability to inexpensively alter DNA, even in very simple ways, will lead to better food and better medicine. Imagine a treatment that alters a pathogen such that it attacks cancer cells in the human body. It sounds outlandish, but that is essentially what your immune system does with disease. Of course, the ability to “correct” genetic defects will have an enormous impact on human health.

It’s easy to fall into the science fiction fantasy stuff when thinking about these topics, but small things can have a huge impact on human behavior. Improvements in sanitation, food production and basic medicine greatly altered the human condition. Just look at the impact of life expectancy. If lifespans were still as they were a century ago, things like pension costs and health care would not be topics in politics. It is because we can live, and live vigorously, into our 70’s that these issues are now major topics.

That’s why this gene editing technology is such a big deal. Up until very recent, the consensus in science was that we were generations away from having the ability to edit human DNA. All of a sudden, the future is now and the rush is on to be the first to alter an actual human embryo and bring it to term. It also means that science will suddenly shift from the purely theoretical to the practical. The first guy to figure out how to fix defects in something as frivolous as purebred dogs will become very rich and very famous.

There’s another aspect to this that is probably more important than the potential impact on human biology. What this technology is doing is bringing to center stage a truth about humanity that our betters have been trying to suppress for generations. That is, what we are is what we inherit from our parents. What they are is what they inherited from their parents. Each of us is the result of thousands of generations of breeding. Our physical and cognitive traits are the result of that long ad hoc experiment.

At a basic level, people know this. Anyone who is familiar with human children knows that they look and act like their parents from an early age. But, people don’t think to hard about this stuff and our rulers work to keep us from thinking about how this scales up. If a white man is the result of thousands of generations of white people, that means the African is the result of his ancestors evolving in Africa. It’s not a long walk from there to accepting that race is real. That’s why this thinking is a mortal sin on our age.

This becomes increasingly difficult when it becomes more common for a doctor to use ideas and techniques from genetics to better serve his patients. The old gag about race is that race is a social construct until you need a bone marrow transplant. Not a lot of people have that talk with their doctor, but imagine a world where everyone has a genetic realism talk with their dog breeder. When you know Rover had a known defect in his breed fixed by a vet at the canine gene clinic, talking about biological reality gets a lot easier.

As people come to accept the reality of gene editing, even if it is just to make better dog breeds, it is much more difficult to maintain the mythologies of the blank slate.  Once people come to accept that things like IQ and personality traits are determined by our genes, the blank slate is finished. Even if people don’t accept genetic determinism, they will accept testing for IQ and personality traits to fill engineering positions. In other words, strides in genetics will restore a more sober understanding of the human condition.

This is the negation of the core belief of our ruling elite, but it is telling that our rulers seem to be going in the opposite direction. As science makes clear the realities of human biology, our rulers scream ever louder to the contrary. Instead of simply ignoring the new information, they are waging pogroms too root out anyone not fully committed to their biological denialism. Every week were treated to some new scandal where a heretic is brought forth and punished for acknowledging reality.

It’s common to compare our current age to the scientific revolution. Galileo is a compelling figure. That does work at some level, but what we are really experiencing is something like what happened in the Roman Empire, prior to Constantine. As the people began to embrace the new religion, the rulers tried to crack down on it. This only made the new religion more popular. The great insight of Constantine was to recognize the strategic advantage that was available to the first ruler who embraced the new religion.

That’s probably what awaits us. Science is moving along faster than the the current throne and altar cabal can follow. Some clever politician is going to embrace biological realism and ride it to victory over the prevailing orthodoxy. The first politician to say “Of course men and women are different” and not get run out of town will be the snowflake that sets off the avalanche. Regardless, breakthroughs like CRISPR are about to shake the foundation of our culture. The blank slate’s days are numbered.

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Saml Adams
Guest

Ein Volk, ein Reich, ein Google.

Bruno the Arrogant
Guest

Google should invite Anders Breivik to the company picnic. He could cure what ails them, but fast.

Member
Race realism is right there for anyone to see. It is reasonable to expect and hope that the scales will fall from the eyes of rose around us, but there is no guarantee that the scales will fall. Man has lived in denial of facts since the beginning of time. Are things going to change now? Simply because there are new facts? In the case of Constantine it is evident that he was not simply making a calculated political triangulation. Scholars have been trying to prove that for a long time and the evidence just isn’t compelling. Either he really… Read more »
Glen Filthie
Guest

You are correct to have reservations Doc… but to me, the signs are everywhere. Donald Trump was elected despite the politically correct blank slate state that opposed him. Moldilocks got punched out. The New York Times can only sell newspapers to idiots and has had to downsize – and they aren’t finished with that yet.

The wheels are coming off that short bus, and to me… it LOOKS like there’s a light at the end of this dark tunnel.

paul
Guest

Yes, Glen, scientific reality is reality, but the truth is what they want it to be.

jbspry
Guest

“We must respect the other fellow’s religion, but only in the sense and to the extent that we respect his theory that his wife is beautiful and his children smart.”
-H.L. Mencken-

And that goes double for theories on race:
https://www.youtube.com/watch?v=w0lyYj2MPg8

Glen Filthie
Guest
We might be seeing that snowflake right now with that guy at Google that dared all the other SJW snowflakes by addressing the truth. I’ve heard from the internet that the man is a genius. He’s a game theory expert and some are positing that he released that memo knowing full well in advance that he would get canned – and then be set up for a slam-dunk lawsuit with a tasty pay out and increased career options and potential. I think they may be right- people are getting fed up with the blank slate and the blank minds that… Read more »
Saml Adams
Guest

Something about this Google situation has that “won’t go away” feeling.

Karl Hungus
Guest

James Damare is the self-immolating street vendor (re:Tunisia) that will set off a huge reaction. For a start, it exposes the big tech companies as hollow; they will not be producing Skynet.

Alex
Guest

Yes his filing with the NLRB was pure genius.

Dan Kurt
Member

See James Damore in living color talk with Stefan Molyneux for 45 minutes: https://www.youtube.com/watch?v=TN1vEfqHGro

Dan Kurt

james wilson
Guest

Disappointing. Maybe Peterson will do better with him. Kudos to the kid for stepping up but I do not see that he understands what he has stepped into. He is convinced that there are two sides and that they need to talk to each other.

Dan Kurt
Member

I agree with you. Have flagged the Peterson interview for later. Damore may be smart but he strikes me as being unschooled and struggling with developing a world view that is logical. He needs to do a lot of reading and thinking then start paring down his assumptions of givens. He will probably do just fine in the long run.

mark auld
Guest

Thanks for the link to the Moly interview.

Calsdad
Guest

He’s walking the path. Have patience and let it play out.

He just got a red pill. It’s not going to all happen in one day.

Calsdad
Guest

In my experience the people who are really smart – have a hard time with getting told that the guy they work directly with and know is a complete idiot – is as smart as them.

Once a bunch of other idiots band together and start trying to beat down the smart guy – all hell usually breaks loose.

Member
Yet the managerial class is utterly dependent upon intelligence and aptitude tests with names like SAT, GRE, LSAT, FSWE, etc. to replenish their ranks. What’s your take on the disconnect, Zman? I go back and forth between guilt (I won the lottery of life and the poor bastids I went to high school back in Possumtrot are still there either working their finger to the bone or committing suicide on the installment plan with drugs) or cognitive dissonance (they are so bought into the radical egalitarian ideology of their class that they have to proclaim their adherence of the same… Read more »
Eclectic Esoteric
Guest

The first step in the journey of a thousand miles may be CRISPR. The second step may be a quantum leap. If genetic biologists manage to isolate and edit the charlatan gene, the swamp will drain itself.

mark auld
Guest

More of the same on the current thread at VD’s blog,and where it stops,nobody knows…we do live in interesting times. I’m still surprised by the size and heft of the SJW movement.

Dan Kurt
Member

re: “I’m still surprised by the size and heft of the SJW movement.” mark auld

Did you go to college during the past 60 years? Did you watch TV and read the popular news magazines, e.g. Time & Newsweek, and read the “opinion magazines,” e.g. New Yorker, Atlantic, Scientific American, etc,, during those years? Did you attend church during those years? If you did, you shouldn’t be surprised.

Dan Kurt

mark auld
Guest

Yes to most all sir, but being a reality based organism, I assumed most people would know B.S. when they stepped in it…my bad.

cerulean
Guest

I was an avid reader of Scientific American until it did a review of the Bell Curve. I was amazed. The review fastened on some minor point of the book and gave the authors holy hell for it at great length. Of course, the reason was the reviewer didn’t like the Realism in the book.

That was when I started being less naive. It’s been a long journey.

Karl Hungus
Guest

murray is a cuck; fukk him.

cerulean
Guest

“This [realism] is the negation of the core belief of our ruling elite, ”

The ruling elite are quite realistic. They do not believe in the blank slate for a second. They just want the rest of us to believe in it.

Guest
Guest
Never underestimate the capacity for mass self-delusion. Witness global warming, aka, climate change, aka climate variation. It’s undisputed that: 1) the Earth’s temperature is well within historical norms predating man-made production of atmospheric carbon through widespread burning of fossil fuels; 2) the Earth is cooler now than in numerous historical warm periods, including the medieval warm period; 3) only “adjusted” data indicate a current warming period–the raw data does not; and 4) fluctuations in the Earth’s temperature correlate nearly perfectly with solar activity cycles. Any rational person evaluating the data would conclude that even if atmospheric carbon is, in theory,… Read more »
Karl Hungus
Guest

disagree; collapse is in progress now. will be measured in months, not years.

TomA
Guest

The poor quality of our political and cultural leadership is a manifestation of anti-evolution. For most of our specie’s long history, we selected the best (smartest/strongest) among us to lead because that kept the tribe alive. We now select charlatans who lead us into being evermore stupid. You can pray for a messiah, but history suggests that this problem is usually solved by a population collapse.

mark auld
Guest

The N.Koreans seem bent on proving you right.

primi pilus
Guest
Do we really want humans to have this capability and power? A slide toward delusion, fantasy and (socially-accepted) madness seems to be the standard of our betters, throughout human history. Absent strict, non-human-controlled forces to conform the construction of our minds, and our behavior, to some reality principle, the swirling hologram of our minds seems capable of being bent to any form and inclination. A generation back, who’d have thought our “best” would be protecting and celebrating soldiers who think they are the opposite sex … or some sex of their own construction. Both have become unmoored. So we put… Read more »
Member

The joke I tell my friends is that the number of Liberals who switch from pro-abortion to pro-life will shift dramatically if scientists ever discover a gay gene. Odds are, this won’t happen, as preferences aren’t the same thing as traits I don’t think. But, it’s still fun to contemplate the ramifications.

The other problem, as long as we’re thinking futuristically, is “The Incredibles” problem. The great line from Syndrome in that movie is, “And when everyone is super. No one will be.”

Then what?

https://www.youtube.com/watch?v=A8I9pYCl9AQ

Herrman
Guest

Long before the blueprint for a designer baby is completed, there will be a blueprint for a designer virus. At that point we get to learn whether intelligence is actually selected for. I have my doubts.

WetBurn
Guest

“Our rulers scream louder to the contrary” because deep down most of them know they are not worthy. Being born to the right family or being socially connected will no longer entitle them to be part of the elite.

SpongeBob
Guest
In the vein of race realism, we desperately need to realize that any form of welfare is functionally a breeding program regardless of whether or not that is the intent of such. Just look at modern welfare, it has functionally been a breeding program for the low IQ end of the population while the high IQ end is functionally penalized to fund the low IQ breeding program (welfare) if a society is going to have any control over its biological destiny welfare by be tied to reproductive rights, i.e. if you accept welfare you accept the requirement of statutory birth… Read more »
Anonymous White Male
Guest
“This is the negation of the core belief of our ruling elite, but it is telling that our rulers seem to be going in the opposite direction. As science makes clear the realities of human biology, our rulers scream ever louder to the contrary. Instead of simply ignoring the new information, they are waging pogroms too root out anyone not fully committed to their biological denialism. Every week were treated to some new scandal where a heretic is brought forth and punished for acknowledging reality.” I don’t think this is what ((((our rulers)))) are doing. They do not believe in… Read more »
Dutch
Guest
Quite a few commenters here are coming to roughly the same conclusion from different directions. The powers that be know that most of them won their power and influence lottery by birth or circumstance, not by merit. They have set themselves to bringing the merit-based powerful ones into the fold. Setting people against other people, dumbing down the average person, and promoting the blank slate are all tools in their toolbox. Google appears to be the point where the powers that be collide with the smart merit-based people who are not buying what they are selling. Beer and popcorn at… Read more »
Alzaebo
Guest

Yes, but for so few to do so much!

If Narrative is such a powerful tool, imagine what they’ll do with CRISPR.

(As the ancient prophecy says- perfected bodies in a reborn world of beneficient hegemons: stern but just…)

Alex
Guest

“The first politician to say “Of course men and women are different” and not get run out of town will be the snowflake that sets off the avalanche.”

I think this trend is starting to break, especially after the recent Google engineer memo. His subsequent firing got some people saying out loud in the MSM, “Its ironic that Google wants diversity in everything but thought…”

SpongeBob
Guest

ZMAN,

It cascades into everything. Would you want to use a black or Hispanic doctor when you realize they are held to lower standards then White or Asian doctors?

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TWS
Guest

Yikes!

Dan Kurt
Member
Personal anecdote on topic: This past winter my wife and I relocated to Arizona from the North West. The climate was of low humidity compared to ere we lived for 40 years. After a few months my wife developed weakness, mental slowing and confusion, and fell three times. I took her to an ER. She saw an ER physician who examined, took a history and ordered blood tests. She was admitted to the hospital and stayed for five days when she demanded to be discharged. While there she was under the care of a hospitalist, an internist, and was also… Read more »
Ryan
Guest

The first application of this technology will be to the minor variations in genes that are harmful in and of themselves but confer resistance to malaria. A couple dozen of them are know, the most famous is the mutation that causes sickle cell anemia.

On the whole, one of my biology professors in college told the class “most people see the movie Gattaca as a dystopia, but I see it as a social paradigm.”

paul
Guest

Yes, a good no nonsense look at socio and bio genetics. Hard to believe the progressives are hanging on to the social construct theories.
Q= What’s more regressive than a progressive?
A= An unreconstructed progressive

Paul Bonneau
Guest

Race certainly does exist, but one can make more from that fact than it really deserves. Race came about through separation, and guess what? That separation is shrinking, if not quite completely gone. What race is Obama?

As to the opinions of the ruling class, they will evolve as society absorbs the new information about race. They don’t really care what the current racial orthodoxy demands; they only care about staying in power and maintaining their parasitic existence. If that means they may someday have to chuck their anti-racist point of view, it will be done without regret.

james wilson
Guest

A little arithmetic would go a long way here.

Karl Hungus
Guest

obama is of the mongrel race.

Dutch
Guest

As Damore takes pains to point out, it is not about race or gender, it is about the individual. Under the current circumstances, this argument is revolutionary. It shouldn’t be, but it is.

When you have built the entire social order upon the blank-slate attitude that ignores the individual, the social order is ripe for a takedown. The takedown appears imminent.

SpongeBob
Guest

It is about both race & gender when you are making policies for large groups.
comment image

The majority of blacks and hispanics cannot constructively function in a western or asian culture the do not have the personality traits or the intelligence levels needed.
You must understand both scales, the population, and the individual. Doing so would tell you that most companies like google would realistically be white and asian males who are generally introverted. There would be nothing extraordinary or concerning about that any more so than having mostly 7 ft blacks in the NBA.

TWS
Guest

We’ve always had and always will have a place for people regardless of IQ. The problem is when you try to fit people into slots based on the percentage of their race in the population.

There is nothing wrong with low IQ folks we just have to socialize them and make sure we don’t import competition for the left half of our bellcurve.

Compsci
Guest

This conclusion doe not take into account AI and automation in our increasingly technological and high tech (read high IQ) society. There will be increasingly less and less room for the left side of the Bell Curve folk to flourish and prosper.

TWS
Guest

Of course I took automation and technology into account. I saw most of my neighbors put out of work due to a changing world.

I am old enough to remember when a trip to the service station had three guys taking care of your car. We have been promised robots and automation since before I was born.

Even if everything comes to pass as the futurists expect there will always be a left half of the bellcurve and with a little compassion and insight we can help them and us.

james wilson
Guest

I question one detail of that bell. It is my incomplete understanding that East Asians, like women, are less prone to occupy both extremes of the curve. The average is higher but the extreme right end is crimped.

Al from da Nort
Guest
There is just a minor problem or two of bio-engineering. The genes on both sets of chromosomes (for the most part) would have to be corrected _before the first embryonic cell divides_. Right now there is no obvious path to reliably correcting any selected gene on the same chromosome(s) in every cell in multicellular organisms, including a growing embryo. Plus all genetic testing is destructive.* There is speculation that some sort of virus could be developed or coopted for this task. Anyone who thinks that contriving a virus or whatever that can change *all* your chromosomes once you have started… Read more »
SpongeBob
Guest
There is speculation that some sort of virus could be developed or coopted for this task. Anyone who thinks that contriving a virus or whatever that can change *all* your chromosomes once you have started growing or even all your chromosomes in a certain type of cell is a good idea, even were it easy/possible, is borderline crazy. Such an agent would most likely be fatal in situations that are not *very* highly controlled and it *will* get loose. Fission reactions are one hell of a way to just boil water!!!!! A minor accident can easily be fatal or contaminate… Read more »
TWS
Guest

Crispr can’t be used in the US to fix domestic animals. The law made it impossible. No reason except they do not want to lose control so for now, there is only a few animals that can be sold as pets.

D&D Dave in the bubble
Guest
D&D Dave in the bubble

The banter from the LGBQTDIZUEIAWIOQF community will be interesting since they insist that being homosexual is not a choice, they are born that way. Watch the instant meltdown of the left when scientist say they’ve identified the gene that determines if the person will be homosexual. transexual, bisexual, bizzaresexual, etc. With a little alternation to that gene, no worries, that baby will now be a heterosexual.

Watch you’ll see a 180 degree turn from the left why this type of science is dangerous and we should not be tampering with nature.

edmg
Guest

Sorry, that was yesterday’s Narrative. Today’s Narrative is that anyone can be whatever they want themselves to be.

Member

Another problem with bio-engineering is determining what sort of person(s) we actually need A world populated entirely by Mensa members may seem like a good bet – until you have attended a few Mensa meetings, that is. Any society or corporation needs a selection of both planners, managers, and workers, Indians as well as Chiefs.A friend in Moscow told me the trouble with the Soviet Union was too many rocket scientists and not enough plumbers.

TWS
Guest

Society needs all types. We’re not warrior monks or worker bees. We need all of us.

jbspry
Guest

Once we are able to manipulate our genetics with a view to eliminating “defects” our evolution will cease and we will stagnate and ultimately perish.
Presuming, that is, that we do not become wise enough and knowledgeable enough to detect, identify and allow for every minutest alteration in our environment and select in favor of it, as “evolution unchained” seems to do.

Mike
Guest

So if I read this right
Once the unwashed approve of their pets being fixed genetically we can get approval for gmo’so
The future looks good

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